Reproductive System (Male and Female) Practice Questions

Last Updated on March 25, 2025

Reproductive System (Male and Female) Practice Questions For Physician Assistant Exam PANCE. This is sample quiz test consists of 20 multiple-choice questions on the Reproductive System (Male and Female).

The official questions from the reproductive system are 7%. The tests enable the production of offspring through sexual reproduction. Uterus; ovary; cervix; vagina/vulva; menstrual disorders; menopause; breast; pelvic inflammatory disease; contraceptive methods; infertility; uncomplicated pregnancy; complicated pregnancy.

Reproductive System (Male and Female) Practice Questions

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Reproductive System Practice Questions For Physician Assistant Exam

Reproductive System (Male and Female) Practice Questions
Physician Assistant Exam
Total Items: 20
Time Limit: NA

1) A 17-year-old female presents to the emergency room complaining of pelvic pain associated with vaginal discharge. She became sexually active for the first time 2 months ago. Examination reveals cervicitis with a thick yellow discharge. Bimanual exam reveals cervical motion tenderness. Laboratory examination reveals a quantitative Beta hCG and a WBC of 12,000. What is the most likely diagnosis?

2) A 55-year-old female presents with a unilateral, firm, non-tender breast mass detected on screening mammogram. Further imaging suggests microcalcifications. Which of the following is the most likely diagnosis?

3) A 30-year-old female presents with severe right lower abdominal pain and adnexal tenderness. A pelvic ultrasound reveals a 3-cm cystic structure on the right ovary with some free fluid in the pelvis. The pain began abruptly after exercise. Which of the following is most likely?

4) Administration of levonorgestrel/ethinyl estradiol can prevent the occurrence of which of the following?

5) A 25-year-old female who is 36 weeks pregnant presents to the emergency room with vaginal bleeding. Her husband reports that she suddenly started with severe persistent abdominal pain and severe bleeding 20 minutes before presenting to the emergency room. Her prenatal care has been inconsistent, but during most of her visits she has been hypertensive. What is the most likely diagnosis?

6) A 20-year-old female presents to the emergency room with the complaint of pelvic pain, vaginal bleeding, and nausea. Physical exam reveals an adnexal mass on the right. Which of the following diagnostic modalities is the LEAST appropriate?

7) The HPV vaccine is commonly administered to prevent which of the following disorders?

8) Which of the following medications is an abortifacient?

9) A 23-year-old female is found to have a painless ulcer on her labia. The ulcer has a clean base and indurated borders. Which of the following organisms is the most likely cause?

10) A 3-year-old boy presents with his mother to the ER with complaints of sore throat, fever, and drooling that came on very suddenly. His mother reports that he is not up-to-date on vaccinations. Examination reveals a febrile, well-nourished male who is sitting propped up on his hands with his tongue sticking out. What is the NEXT most important step in treating this patient?

11) Which of the following refers to mild contractions that occur after the sixth week of pregnancy but do not signal the start of labor?

12) A 67-year-old male complains of difficulty initiating urination, a weak urinary stream, and nocturia. Digital rectal exam reveals a diffusely enlarged, rubbery prostate. PSA is mildly elevated. Which of the following is the most likely diagnosis?

13) A 32-year-old pregnant female is at 11 weeks gestation and complains of severe nausea and vomiting. She has lost 5% of her prepregnancy weight. Labs reveal ketonuria and mild electrolyte disturbances. Which of the following is the most likely diagnosis?

14) An 18-year-old female G1P0 is 37 weeks pregnant. She presents to the emergency department complaining of headache and edema in hands and feet. Examination reveals BP of 150/80. Urinalysis reveals 2+ protein. What is the most likely diagnosis?

15) Sildenafil is commonly used to treat which of the following disorders?

16) A 35-year-old female of Middle Eastern descent presents to her gynecologist with complaints of genital ulcers. She has also had oral ulcers, decreased visual acuity, and arthralgias. She denies any extramarital affairs and her husband has been asymptomatic. Examination reveals oral stomatitis and ulcers on the external genitalia. What is the most likely diagnosis?

17) A 29-year-old G2P1 female at 36 weeks gestation presents with sudden-onset painless vaginal bleeding. There is no fetal distress on monitoring, and ultrasound shows a placenta covering the internal cervical os. Which of the following is the most likely diagnosis?

18) A 43-year-old female with two healthy children is diagnosed with a complete hydatidiform mole (gestational trophoblastic disease). Which of the following procedures is required to treat this condition?

19) A 28-year-old female with a history of pelvic inflammatory disease presents to her PCP with a history of irregular periods. She states that her period was one week late and then started one week ago and has not stopped. She also complains of pelvic pain and dizziness. Examination reveals a right adnexal mass. What is the most likely diagnosis?

20) A 25-year-old female presents with lower abdominal pain, adnexal tenderness, and cervical motion tenderness. She reports a new sexual partner within the last 2 months. Which of the following diagnoses is most likely?

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